Catalog number: X2335B
Name: Roundabout homolog 1 antibody ROBO1 - Blocking Peptide
Price: 168.00 EUR
Size: 50 μg
Category: Proteins & Peptides
Long description: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development. Defects in ROBO1 may be a cause of breast and lung cancer. ROBO1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.
Antibody come from: Synthetic peptide derived from human FLAP protein.
Other description: Provided as solution in phosphate buffered saline.
Clone: not specified
Antigen-antibody binding interaction: Roundabout homolog 1 antibody ROBO1 - Blocking Peptide
Antibody is raised in: Rabbit
Antibody's reacts with: Human
Antibody's reacts with these species: This antibody doesn't cross react with other species
Antibody's specificity: No Data Available
Application: Western Blot
Antibody's suited for: For use with FLAP polyclonal antibodies (Cat. No. X2318P & X2350P).
Relevant references: 1. Dixon, R.A.F., et al. 'Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis.; Nature 343:282-284(1990)._x000B__x000B_2. Helgadottir, A., et al. 'The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke.; Nat. Genet. 36:233-239(2004).
Protein number: see ncbi
Warnings: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Properties: If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.blocking peptide
Test: You can block the antibody by the specific target amino acid sequence of peptide.
Description: Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
French translation: anticorps